In the world of nootropics, Piracetam is nootropic compound that millions of people around the world use to help to give them a cognitive boost.
The compound has been used to treat cognitive issues, and according to meta-analysis of human subjects, the piracetam is capable of improving overall cognition when it was used by people who have suffered a decline in their cognitive abilities as a result of old age.
Today, we are going to give you an in-depth look at piracetam so you have a better understanding of what it is, the benefits, possible side effects, and why you may or may not want to include it with your nootropic stack.
You could say that piracetam was the pioneer for the racetam class of nootropic drugs.
The compound is also known as Nootropyl or UCB6215, and it’s a synthetic compound that was developed by UCB Pharma in Belgium in 1964. It’s main function is to enhance the brain’s function and it is the basic racetam molecule.
It shares a similar structure to the neurotransmitter GABA. Chemically, it is similar amino acid pyroglutamate--the only difference between the two is a solitary side change. The compound has been prescribed to people under many different names over the past for decades. These alternate names include:
Today, the compound can be used to treat age-related decline in cognitive abilities while giving young, healthy minds a cognitive boost.
There has yet to be a definitive answer in regards to how piracetam works. It is believed that it improves the permeability of cell membranes which leads to improved delivery and dispersal of oxygen to the brain. It can also increase circulation in the neural tissues.
There is a secondary neuroprotective effect that helps structures like synapses and neurons. The enhanced circulation keeps the tissues healthy and well nourished, making the structures protected from normal damage and decay that occurs from aging.
The compound also helps to remove waste matter from cells much quicker than without. The health of the cell’s membrane is important because it prevents hypoxia and can also protect the brain against conditions that may occur as a result of lack of oxygen, such as strokes.
Piracetam will affect glucose levels in the brain, causing increasing the rate at which glucose is metabolized, resulting in higher mental energy and even feelings of being more alert.
Piracetam is a supplement has an impressive list of benefits for those who take it. We want to point out that piracetam may not work for everyone, therefore before taking the supplement, you should always consult your doctor.
With that said, let’s look at benefits of taking the supplement.
There have been studies that shown patients who have had progressive and/or chronic lack of blood flow to the brain have benefitted from taking piracetam. The supplement shows positive effects in concentration, intellectual function, and memory.
When a patient who have had a 12gram injection of piracetam before and/or after bypass heart surgery have shown signs of improved cognition and it also prevented neurodegeneration. Unfortunately, those who had open heart surgery and had the shot, the piracetam didn’t prevent cognitive decline.
When the supplement was given to the hippocampus of rats who were experience alcohol withdrawal, there was a delayed loss of neurons. It also has been shown to increase synaptic reorganization and synapses in those rat who have gone through alcohol withdrawal.
Over the course of 30 years’ worth of research, piracetam has proven to be an effective treatment method for those who experience cognitive impairment. It’s also been shown to increase short term memory only after 14 days of taking 400mg per day in healthy elderly patients.
People who have suffered from depression have reported to feel less depressed, engage in spontaneous activity, and even increase speed of activity. These patients took about 2,400mg per day over a two month period to achieve these results.
Piracetam has the ability to reduce the symptoms one may experience that are related to schizophrenia. The compound protects glutamatergic receptors in the brain and reduces instances of involuntary movement.
Over a three week trial period, patients who suffer from dyslexia have shown an increased ability to learn verbally by 15 percent over those who were given a placebo.
Patients who were healthy experienced 8.6 percent improvement. Students who were given 3.3gm per day over a 36 week period exhibited increased reaction time and the ability to recognize test prompts related to language.
Piracetam is able to reduce pain in mice by decreasing the production of cytokine. It also prevents toxin induced reduction of glutathione.
When soldiers who have been exposed to ear-damaging gunfire were immediately given a combination of piracetam and prednisone, 65 percent of them were able to preserve their hearing. 23.3 percent were able to able to preserve their hearing if they were treated within 24 hours.
Patients who suffer from epilepsy have shown incredible results in the first, sixth, and twelfth month of treatment.
Its recognized that doses differ from user to user, but the average dose of piracetam is 1,600 mg, three times per day. This is going to vary depending on the age of the user, as children are going to take less. The recommended dose and the reason for taking the supplement will also have an impact on the dose.
There is a wide range of effective dosages, with 400 mg being the lowest. Those who have never taken any form of nootropic may need to increase the dose at first just to feel the full effect.
It will take between 1 to 4 hours in order to feel the full effects, so you will want to map out your day and decide when the best time would be to take it.
Nootropics are often stacked with one another to achieve maximum desired effects. When you combine it with elements that complement each other, you can expect the overall effect to be that much greater. Since piracetam is non-toxic and the side effects are minimal, you can stack it with no problem.
Here are three great stacks people like that include piracetam:
This stack is great for supercharging your cognitive abilities. Choline effects the memory, your ability to reason with logic, and concentrate. Piracetam will already use the choline already stored in the body, so adding more choline will balance this effect.
We’ve all had instances when you feel like your brain is a bit foggy. This combination is going to help enhance mental acuity and clarity. Piracetam boost brain circulation and the extra energy boost from the caffeine will help users focus, while the choline will help support neuroplasticity.
When you feel like you’re having troubles remembering things, combine piracetam and aniracetam and/or oxiracetam. This dynamic combination will help boost your memory and concentration, while creating an incredible racetam experience.
As wonderful as piracetam may seem for those who need a cognitive boost, there are some possible side effects that you should be aware of:
Piracetam is one of those supplements that can take you from being regular you and make you feel like you are ready to tackle that long to-do list.
It is great for keeping you focused and helping you concentrate when you really need to, but it also can help people who suffer from a variety of maladies that otherwise would make their lives more difficult.
If you want to try piracetam, we recommend consulting your doctor first so they can weigh in and make dosage recommendations.